How many employees does Septerna Inc have?

Septerna Inc reported 130 employees for the fiscal year ending Dec 2025, in the annual report it filed on March 9, 2026. That is up 73.3% from a year earlier.

What is Septerna Inc's revenue per employee?

Septerna Inc brought in $46.0M of revenue in fiscal Dec 2025, which is $353K per employee. That ranks 69 of 108 companies we track in Biotechnology, where the median is $459K.

Where do these numbers come from?

Employee counts and revenue are taken from each company's own annual report (Form 10-K). Open roles are counted from the company's public job board where we have matched one. Companies report headcount once a year, sometimes rounded, so small changes can be noise.

Company data

Septerna Inc employees and revenue per employee

SEPN · Biotechnology · $1.73B market cap

Septerna Inc had 130 employees at the end of fiscal Dec 2025, up 73.3% from a year earlier. Revenue for the year was $46.0M, up 4174.5% from a year earlier, or $353K per employee. Revenue and headcount both grew, and revenue grew faster.

Employees

130

+73.3% YoY

Revenue

$46.0M

+4174.5% YoY

Revenue / employee

$353K

Peer median $459K

Rank in industry

69 of 108

Biotechnology

Headcount against revenue

Both lines start at 100 in the first year we hold, so you can see which one grew faster.

EmployeesRevenueIndexed to 100 in Dec 2024

Hover a year for the numbers.

SEPN employees and revenue by fiscal year
Year ending	Employees	Revenue	Per employee	Staff YoY	Revenue YoY
Dec 2025	130	$46.0M	$353K	+73.3%	+4174.5%
Dec 2024	75	$1.1M	$14K	—	—

Open roles: we have not matched a verified job board for this company yet.

Employees, last six fiscal years

Revenue per employee, last six fiscal years

Septerna Inc against similar companies

The closest industry peers by revenue, from Biotechnology.

Company	Employees	Revenue	Revenue / employee	Shape
FENC Fennec Pharmaceuticals Inc.	35	$44.6M	$1.28M	Hiring into decline
NKTR Nektar Therapeutics	63	$55.2M	$877K	Hiring into decline
TNGX Tango Therapeutics, Inc.	137	$62.4M	$455K	Leaner
SEPN Septerna Inc	130	$46.0M	$353K	Efficient growth
PTGX Protagonist Therapeutics, Inc.	132	$46.0M	$349K	Hiring into decline
NUVB Nuvation Bio Inc.	298	$62.9M	$211K	Efficient growth
KYMR Kymera Therapeutics, Inc.	238	$39.2M	$165K	Hiring into decline
OCUL Ocular Therapeutix, Inc.	325	$51.8M	$159K	Hiring into decline
AGIO Agios Pharmaceuticals, Inc.	539	$54.0M	$100K	Efficient growth

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Questions about Septerna Inc

How many employees does Septerna Inc have?: Septerna Inc reported 130 employees for the fiscal year ending Dec 2025, in the annual report it filed on March 9, 2026. That is up 73.3% from a year earlier.
What is Septerna Inc's revenue per employee?: Septerna Inc brought in $46.0M of revenue in fiscal Dec 2025, which is $353K per employee. That ranks 69 of 108 companies we track in Biotechnology, where the median is $459K.
Where do these numbers come from?: Employee counts and revenue are taken from each company's own annual report (Form 10-K). Open roles are counted from the company's public job board where we have matched one. Companies report headcount once a year, sometimes rounded, so small changes can be noise.

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Source: employee counts and revenue as stated in Septerna Inc's annual reports (Form 10-K), latest filed March 9, 2026. This is data, not a recommendation to buy or sell SEPN.